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Info about Hormone Replacement Therapy

Necessary to know

Hormone replacement therapy (HRT) is based on using estrogen and progestin, while estrogen replacement therapy (ERT) is used without progestin.


Make a survey for precancerous changes of the endometrium before going through the treatment (an annual pelvic exam and an annual endometrial biopsy).Be aware that using only ERT you may enlarge the risk of endometrial cancer. If it is difficult for you to do with the side effects of progestin, use estrogen replacement therapy (ERT). But first of all you should test yourself to find out the normality of the endometrium.


Hormone replacement therapy (HRT), which combines estrogen and progestin, does not have any influences. HRT is usually used for a short-term treatment of menopausal symptoms.

Be calm if you had ever had a hysterectomy, as this condition helps to reduce the risk of uterine cancer.

It is not known if there is a difference in effect both of estrogen and progestin, but many women have a preference in estrogen in spite of its unanimal originality.


Side Effects

For a full list of side effects overlook Drug Reference, but do know that Drug Reference does not refer to physical conditions.
Here you can observe the following common side effects caused by all forms of estrogen, but do know that these side effects often occur with oral estrogen:

- Vaginal discharge;
- Breast tenderness;
- Headaches;
- Fluid retention;
- Weight gain;
- Spotting or darkening of the skin, particularly on the face;
- Deep venous thrombosis;
- Nausea;
- Pulmonary emboli;
- An increased growth of preexisting uterine fibroids or a worsening of endometriosis (rarely).
- skin irritation caused by estrogen patch (transdermal estrogen).
Be aware that such symptoms as headaches, nausea, fluid retention, weight gain, and breast tenderness, may be away after several weeks.

You should change an estrogen ring after 3 months passed. In case of falling out the ring during these 3months of treatment, just rinse the ring with warm water and insert it again.

If you are a woman with liver or gallbladder disease, you may make use of vaginal cream.

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